Organ

Relative organ weight changes (g/100g body weight)

Group

Both male & female

Male

Female

Heart

Control

0.36 ± 0.02

0.37 ± 0.03

0.34 ± 0.02

1 mg/Kg bwt

0.41 ± 0.01 (0.57)

0.40 ± 0.02 (0.97)

0.43 ± 0.02 (0.55)

5 mg/Kg bwt

0.43 ± 0.02 (0.33)

0.44 ± 0.02 (0.73)

0.42 ± 0.03 (0.61)

20 mg/Kg bwt

0.50 ± 0.02 (0.01*)

0.48 ± 0.01 (0.24)

0.49 ± 0.05 (0.06)

5000 mg/Kg bwt

0.48 ± 0.09 (0.10)

0.52 ± 0.20 (0.25)

0.43 ± 0.03 (0.65)

ANOVA values

0.01*

0.16

0.11

Kidney

Control

0.38 ± 0.02

0.37 ± 0.02

0.40 ± 0.05

1 mg/Kg bwt

0.46 ± 0.02 (0.04*)

0.48 ± 0.02 (0.03*)

0.44 ± 0.01 (0.84)

5 mg/Kg bwt

0.45 ± 0.01 (0.14)

0.44 ± 0.01 (0.23)

0.45 ± 0.01 (0.69)

20 mg/Kg bwt

0.49 ± 0.02 (< 0.001)

0.45 ± 0.02 (0.11)

0.54 ± 0.03 (0.03*)

5000 mg/Kg bwt

0.49 ± 0.05 (0.03*)

0.48 ± 0.09 (0.11)

0.50 ± 0.07 (0.34)

ANOVA values

0.004*

0.04*

0.04*

Lung

Control

0.74 ± 0.07

0.63 ± 0.04

0.88 ± 0.12

1 mg/Kg bwt

0.89 ± 0.05 (0.66)

0.89 ± 0.07 (0.01*)

0.89 ± 0.07 (1.00)

5 mg/Kg bwt

0.93 ± 0.09 (0.43)

0.74 ± 0.04 (0.49)

1.11 ± 0.15 (0.73)

20 mg/Kg bwt

0.86 ± 0.07 (0.80)

0.74 ± 0.03 (0.48)

1.00 ± 0.13 (0.96)

5000 mg/Kg bwt

0.92 ± 0.09 (0.68)

0.79 ± 0.07 (0.42)

1.06 ± 0.11 (0.94)

ANOVA values

0.50

0.02*

0.67

Liver

Control

4.08 ± 0.14

4.06 ± 0.18

4.10 ± 0.28

1 mg/Kg bwt

4.05 ± 0.11 (1.00)

3.95 ± 0.09 (0.99)

4.21 ± 0.27 (1.00)

5 mg/Kg bwt

3.87 ± 0.11 (0.86)

3.67 ± 0.11 (0.56)

4.06 ± 0.16 (1.00)

20 mg/Kg bwt

4.29 ± 0.16 (0.84)

4.03 ± 0.23 (1.00)

4.60 ± 0.11 (0.52)

5000 mg/Kg bwt

4.09 ± 0.31 (1.00)

3.74 ± 0.01 (0.86)

4.45 ± 0.58 (0.90)

ANOVA values

0.31

0.46

0.33