Patient

parameter

B. G.

E. R.

H. A.

M. F.

Average ± St Dev

W (kg)

85

65

110

76

84 ± 19.2

* $\alpha$ (h⁻¹)

4.0073

4.8501

3.5422

7.8375

5.0593 ± 1.9296

* $\beta$ (h⁻¹)

0.2613

0.3327

0.1968

0.2911

0.2705 ± 0.0572

$k_{12}$ (h⁻¹)

2.1958

2.6317

1.7450

5.1062

2.9197 ± 1.5020

$k_{21}$ (h⁻¹)

1.2003

1.1591

1.5420

1.4663

1.3419 ± 0.1906

$k_{10}$ (h⁻¹)

0.8725

1.3919

0.4520

1.5561

1.0681 ± 0.5036

$V_1$ (L)

9.00

8.84

18.96

8.18

11.25 ± 5.16

$V_2$ (L)

16.46

20.07

21.46

28.50

21.62 ± 5.04

$V_{d,1}$ (L)

25.46

28.91

40.42

36.68

32.87 ± 6.88

AUC_ss (ng∙h/mL)

63.68

40.63

58.33

39.26

50.48 ± 12.37

CL (L/h)

7.85

12.31

8.57

12.73

10.37 ± 2.51

$A_1$

0.7493

0.8170

0.5979

0.8443

0.7521 ± 0.1103

$B_1$

0.2507

0.1830

0.4021

0.1557

0.2479 ± 0.1103

$A_2$ (h⁻¹)

−0.2670

−0.2214

−0.2989

−0.1325

−0.2299 ± 0.0723

$B_2$ (h⁻¹)

0.2670

0.2214

0.2989

0.1325

0.2299 ± 0.0723