Conventional Formulation (1% cream)

Test Formulation (1% Liposomecream)

DISK 1

DISK 2

DISK 3

DISK 4

DISK 5

DISK 6

DISK 1

DISK 2

DISK 3

DISK 4

DISK 5

DISK 6

Micrograms of TH in the SC

98.1

27.2

101.6

37.2

20.1

14.7

45.1

132.0

137.3

124.8

49.3

92.9

Micrograms of TH in the VE

2.06

1.40

6.88

16.49

11.73

1.08

4.47

6.82