Characteristics | LVEDP > 15 n = 28 | LVEDP ≤ 15 n = 26 | p-Value |
Surrogate markers for filling pressure |
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|
|
E/E’septal | 16 ± 6.3 | 17 ± 7.6 | 0.967 |
E/Vp | 2 ± 0.9 | 2 ± 0.9 | 0.693 |
IVRT/TE’-TE | 0.4 ± 5.3 | 0.004 ± 6.3 | 0.809 |
Cardiopulmonary function parameters |
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|
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VE/VCO2slope | 31 ± 8.5 | 28 ± 4.6 | 0.047 |
VO2peak (ml/kg/min) | 19 ± 6.1 | 22 ± 6.7 | 0.058 |
VO2Predicted (%) | 81 ± 26.8 | 86 ± 27.6 | 0.499 |
VO2AT (ml/kg/min) | 12 ± 3.3 | 14 ± 3.8 | 0.017 |
Wattmax | 91 ± 29.9 | 110 ± 46.1 | 0.1 |
Heart rate at peak, bpm | 126 ± 17.2 | 122 ± 24.5 | 0.303 |
Syst AP, mmHg | 135 ± 18.1 | 130 ± 11.3 | 0.5 |
Syst AP at peak, mmHg | 179 ± 20.9 | 180 ± 21.5 | 0.683 |
Diast AP, mmHg | 78 ± 10.6 | 79 ± 10.5 | 0.626 |
Diast AP at peak, mmHg | 87 ± 10.6 | 88 ± 10.8 | 0.731 |
Biomarker |
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|
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NT-proBNP (pg/mL) | 463 ± 444.6 | 245 ± 267.2 | 0.048 |
Echocardiographic parameters |
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|
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LVMI/BSA (g/m2) | 142 ± 36.7 | 125 ± 36 | 0.101 |
LAD/BSA (mm/m2) | 25 ± 2.9 | 24 ± 2.9 | 0.114 |
EF (%) | 62 ± 7.8 | 64 ± 7.3 | 0.369 |
S’septal (cm/sec) | 8 ± 1.6 | 9 ± 2.8 | 0.091 |
Flow propagation velocity (cm/sec) | 52 ± 20.5 | 50 ± 14.5 | 0.705 |
E’sep (cm/sec) | 6 ± 1.9 | 7 ± 2.6 | 0.389 |
A’sep (cm/sec) | 10 ± 2.6 | 11 ± 2.6 | 0.21 |
E’sep/A’sep | 0.7 ± 0.3 | 0.7 ± 0.2 | 0.655 |
E/E’lateral | 11 ± 4.4 | 13 ± 6.1 | 0.463 |
Syst AP (mmHg) | 138 ± 18 | 135 ± 17 | 0.421 |
Diast AP (mmHg) | 78 ± 9 | 78 ± 9 | 0.971 |
AP measured during heart catheterization |
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|
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Syst AP (mmHg) | 152 ± 52 | 130 ± 20 | <0.001 |
Diast AP (mmHg) | 69 ± 13 | 70 ± 10 | 0.796 |