Vaccine

Bivalent

Quadrivalent

Nonavalent

VPL

16/18

6/11/16/18

6/11/16/18/31/33/45/52/58

Adjuvant

ASO4 (detoxified form of lipopolysaccharide and aluminium hydroxide)

Aluminium hydroxide

Aluminium hydroxide

Indications

· Precancerous lesions of the cervix, vulva, vagina, anus

· Cancer cervix, anus

· Precancerous lesions of the cervix, vulva, vagina, anus

· Cancer cervix, anus

· Anogenital warts

· Precancerous lesions of the cervix, vulva, vagina, anus

· Cancer cervix, anus

· Anogenital warts

Population and dosage

People 9 - 14 years old (inclusive): 2 doses; 0 and 6 months

People 15 years or older: 3 doses; 0.1 and 6 months

People 9 - 13 years old (inclusive): two guidelines

· 2 doses; 0 and 6 months

· 3 doses; 0.2 and 6 months

People 14 years and older: 3 doses; 0.2 and 6 months

People 9 - 14 years old (inclusive): two guidelines

· 2 doses; 0 and 6 months

· 3 doses; 0.2 and 6 months

People 15 years or older: 3 doses; 0.2 and 6 months

Coverage

70% cancer of the vulva, cervix, vagina, penis, anus, or opharynx

+90% genital warts

+20% cervical cancer