| Organ/Tissue | T1 Control | T2 100 mg/kg Sangrovit® | T3 500 mg/kg Sangrovit® | T4 1000 mg/kg Sangrovit® | Treatment effect P= | ||||
| F | CM | F | CM | F | CM | F | CM | ||
| Skin | 0.50 ± 0.58 | 1.00 ± 0.00 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.75 ± 0.50 | 0.25 ± 0.50 | 1.00 ± 0.00 | 0.8095 |
| Brain | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.25 ± 0.50 | 1.0000 |
| Eyes | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.75 ± 0.96 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.5044 |
| Pituitary gland | 0.50 ± 0.58 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.8637 |
| Thyroid gland | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.50 ± 0.58 | 0.00 ± 0.00 | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.9369 |
| Parathyroid gland | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.5163 |
| Heart | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.50 ± 0.58 | 0.5496 |
| Lung | 0.50 ± 0.58 | 0.75 ± 0.96 | 0.75 ± 0.96 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.8013 |
| Spinal cord | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.9369 |
| Stomach | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.9369 |
| Liver | 0.75 ± 0.96 | 0.50 ± 0.58 | 0.25 ± 0.50 | 1.00 ± 0.00 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.75 ± 0.96 | 0.50 ± 0.58 | 0.9507 |
| Gall bladder | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.7079 |
| Lymph nodes | 0.50 ± 0.58 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.50 ± 0.58 | 0.9369 |
| Spleen | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.75 ± 0.96 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.3664 |
| Pancreas | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.9369 |
| Kidneys | 0.00 ± 0.00 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.4376 |
| Adrenal gland | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.75 ± 0.96 | 0.9369 |
| Bone and marrow | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.50 ± 0.58 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.8871 |
| Marrow smear | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.2288 |
| Duodenum | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.3664 |
| Jejunum | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.75 ± 0.96 | 0.00 ± 0.00 | 0.9459 |
| Ileum | 0.50 ± 0.58 | 0.75 ± 0.96 | 0.75 ± 0.96 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.7395 |
| Colon | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.8013 |
| Caecum | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.75 ± 0.96 | 0.25 ± 0.50 | 0.50 ± 0.58 | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.9459 |
| Thymus | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.75 ± 0.96 | 0.25 ± 0.50 | 0.75 ± 0.96 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.50 ± 0.58 | 0.5796 |
| Muscle | 0.75 ± 0.96 | 0.75 ± 0.96 | 0.50 ± 0.58 | 0.50 ± 0.58 | 1.00 ± 0.00 | 0.75 ± 0.96 | 0.50 ± 0.58 | 0.75 ± 0.96 | 0.4376 |
| Urinary bladder | 0.00 ± 0.00 | 0.50 ± 0.58 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.6549 |
| Ovaries | 0.75 ± 0.96 | -1 | 0.25 ± 0.50 | - | 0.75 ± 0.96 | - | 0.75 ± 0.96 | - | 0.4262 |
| Uterus | 0.50 ± 0.58 | - | 0.50 ± 0.58 | - | 0.50 ± 0.58 | - | 0.75 ± 0.96 | - | 0.8944 |
| Mammary gland | 0.50 ± 0.58 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.25 ± 0.50 | 0.25 ± 0.50 | 0.00 ± 0.00 | 0.6695 |