US Only (Ultrasound Graf Classification Only)

US with CD (Ultrasound Graf Classification with CDa)

≤28 Days

29 - 56 Days

>56 Days

Sig.

≤28 Days

29 - 56 Days

>56 Days

Sig.

(n = 1907)

(n = 720)

(n = 355)

(X2)b

(n = 1907)

(n = 720)

(n = 355)

(X2)b

False Positive (FP)

227 (11.9%)

11 (1.5%)

1 (0.3%)

109.01

***

260 (13.6%)

31 (4.3%)

7 (2.0%)

79.39

***

False Negative (FN)

0 (0.0%)

0 (0.0%)

2 (0.6%)

14.81

***

0 (0.0%)

0 (0.0%)

0 (0.0%)

True Positive (TP)

8 (0.4%)

2 (0.3%)

0 (0.0%)

1.67

8 (0.4%)

2 (0.3%)

2 (0.6%)

0.52

True Negative (TN)

1672 (87.7%)

707 (98.2%)

352 (99.2%)

104.97

***

1639 (85.9%)

687 (95.4%)

346 (97.5%)

77.05

***

Sensitivityd

100.0%

100.0%

0.0%

n/ac

100.0%

100.0%

100.0%

n/ac

Specificitye

88.0%

98.5%

99.7%

n/ac

86.3%

95.7%

98.0%

n/ac

Positive Predictive Value (PPV)f

3.4%

15.4%

0.0%

n/ac

3.0%

6.1%

22.2%

n/ac

Negative Predictive Value (NPV)g

100.0%

100.0%

99.4%

n/ac

100.0%

100.0%

100.0%

n/ac

Positive Likelihood Ratio (PLR)h

8.37

65.27

0.00

n/ac

7.30

23.16

50.43

n/ac

Negative Likelihood Ratio (NLR)i

0.00

0.00

1.01

n/ac

0.00

0.00

0.00

n/ac

Accuracyj

88.1%

98.5%

99.2%

93.62

***

86.4%

95.7%

98.0%

79.39

***