Properties

NCI207113

TCM0004

TCM3282

Human intestinal absorption

+

+

+

Human oral bioavailability

+

−

−

Plasma protein binding

+

+

+

Blood-brain barrier

+

+

+

CYP2D6 binding

−

−

−

Hepatotoxicity^a

0.6250

0.6000

0.6500

Carcinogenicity

−

−

−