Conventional stage

TNM stage

Clinical Manifestations

Treatment

Fifteen Year Survival (%)

A1

T1a

Non palpable tumor, low grade cancer, <5% of prostate involved (Incidental finding at prostatectomy)

Observation

Normal

A2

T1b

Non palpable tumor, high grade cancer or >5% of prostate involved, or both (Incidental finding at prostatectomy)

Total prostatectomy with pelvic lymphadenectomy

30 - 45

B1

T2a

Localized nodule, 1 - 1.5 cm in diameter in one lobe

Total prostatectomy with pelvic lymphadenectomy

50 - 60

B2

T2b

Tumor > 1.5 cm in diameter or more than one lobe

Total prostatectomy with pelvic lymphadenectomy

35 - 45

C

T3, T4

Periprostatic extension

Radiation with or without pelvic lymphadenectomy

20 - 30

D

N+ Or M+

Pelvic lymph node involvement or distant metastasis

Hormonal therapy (LHRH/antiandrogen) when symptomatic. Irradiation for isolated bone pain

0 - 10