| Chemotherapy | Toxicity grade | Gastro-intestinal toxicities | |||||||||||
| Nausea | Vomiting | Diarrhoea | Constipation | Oral mucositis | Abdominal pain | ||||||||
| n | % | n | % | n | % | n | % | n | % | n | % | ||
| cycle 1 | Grade 1 | 29 | 58% | 6 | 12% | 3 | 6% | 7 | 14% | 7 | 14% | 3 | 6% |
| Grade 2 | 2 | 4% | 5 | 10% | 14 | 28% | 0 | 0% | 0 | 0% | 9 | 18% | |
| Grade 3 | 0 | 0% | 0 | 0% | 2 | 4% | 0 | 0% | 0 | 0% | 2 | 4% | |
| Grade 4 | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | |
| Overall | 31 | 62% | 11 | 22% | 19 | 38% | 7 | 14% | 7 | 14% | 14 | 28% | |
| cycle 2 | Grade 1 | 34 | 68% | 8 | 16% | 4 | 8% | 3 | 6% | 4 | 8% | 6 | 12% |
| Grade 2 | 4 | 8% | 12 | 24% | 8 | 16% | 0 | 0% | 2 | 4% | 7 | 14% | |
| Grade 3 | 0 | 0% | 2 | 4% | 5 | 10% | 0 | 0% | 0 | 0% | 0 | 0% | |
| Grade 4 | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | |
| Overall | 38 | 76% | 22 | 44% | 17 | 34% | 3 | 6% | 9 | 18% | 13 | 26% | |
| cycle 3 | Grade 1 | 29 | 58% | 2 | 4% | 3 | 6% | 0 | 0% | 4 | 8% | 3 | 6% |
| Grade 2 | 6 | 12% | 10 | 20% | 9 | 18% | 0 | 0% | 0 | 0% | 10 | 20% | |
| Grade 3 | 0 | 0% | 2 | 4% | 3 | 6% | 0 | 0% | 2 | 4% | 2 | 4% | |
| Grade 4 | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | |
| Grade 5 | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | 0 | 0% | |
| Overall | 35 | 70% | 14 | 28% | 15 | 30% | 0 | 0% | 6 | 12% | 15 | 30% | |