No (ref)

16,350

Yes

2120

1.34

1.195 - 1.492

<0.0001

NCI Comorbidity Score

0 (ref)

10,481

1

4661

0.98

0.900 - 1.065

0.1715

2

1868

1.00

0.885 - 1.125

0.5390

≥3

1460

1.13

0.989 - 1.296

0.0463

RS Assay

No (ref)

15,460

Yes

3010

0.53

0.45 - 0.66

<0.0001

Radiotherapy

No (ref)

7785

Yes

10,685

0.70

0.648 - 0.751

<0.0001