Risk group according to the NCCN guidelines

Entire

population

n = 751

Very low

N = 45

Low

N = 137

p-value

very low vs. low

Age

mean (range)

65.3 (46 - 81)

64.2 (51 - 74)

63.8 (47 - 78)

0.69

Age <65

330 (43.9)

21 (46.7)

74 (54.0)

0.32

PSA*, ng/ml

mean (range)

9.9 (1.1 - 89.0)

5.4 (1.1 - 8.6)

6.3 (3.0 - 10.0)

<0.05

PSA density

ng/ml/cc

mean

(range)

0.32

(0.02 - 3.30)

0.11

(0.05 - 0.15)

0.22

(0.06 - 0.45)

-

Clinical T stage, n (%)

T1c or T2a

T2b or T2c

T3

659 (88%)

84 (11%)

8 (1%)

45 (100%)

-

-

137 (100%)

-

-

-

Biopsy Gleason score, n (%)

≤6

7

≥8

251 (34%)

328 (44%)

167 (22%)

45 (100%)

-

-

137 (100%)

-

-

-

No .of positive cores

1, 2

3, 4

5, 6

≥7

363

230

86

71

45

-

-

-

78

42

10

7

-

Pathological stage, n (%)

pT2

pT3a

pT3b

pN+

498 (66%)

181 (24%)

60 (8%)

12 (2%)

40 (89%)

5 (11%)

-

-

111 (81%)

25 (18%)

-

1 (1%)

0.43

Positive surgical margins, n (%)

308

(41%)

11

(24%)

49

(36%)

0.16

Gleason score

≤6

7

≥8

118 (15.7%)

466 (62.1%)

167 (22.2%)

23 (51.1%)

21 (46.7%)

1 (2.2%)

43 (31.4%)

88 (64.2%)

6 (4.4%)

0.017 for ≤6