Recent findings on Gut-skin and Skin-lung relationships | References |
Gut-lung relationship |
|
The degree of diversity in gut microbiota at birth negatively correlated the tendency to develop to asthma in children in human | [3] |
The disturbance of gut microbiota in mice at 3 weeks of age was found to increase the occurrence of allergic airway inflammation in adult mice | [8] |
The transplantation of fecal microbiota can protect against the pneumonia in microbiota-depleted mice | [10] |
The metabolism of dietary fiber afforded by gut microbiota can influence the extent of allergic inflammation in the airway in mice | [11] |
Lung-skin relationship |
|
The number and/or diversity of gut microbiota at birth is likely to be positively associated with the pathogenesis of skin eczema in human | [2] [3] |
About 1% - 2% patients with lung cancer may develop skin metastases | [13] |
Elderly women with certain matrix metalloproteinase promotor variants demonstrated a higher susceptibility to skin wrinkling and lung dysfunctions | [19] |
About 50% infants who had acute severe bronchiolitis developed dry skin or eczema within 12 months thereafter | [22] |