Recent findings on Gut-skin and Skin-lung relationships

References

Gut-lung relationship

The degree of diversity in gut microbiota at birth negatively correlated the tendency to develop to asthma in children in human

[3]

The disturbance of gut microbiota in mice at 3 weeks of age was found to increase the occurrence of allergic airway inflammation in adult mice

[8]

The transplantation of fecal microbiota can protect against the pneumonia in microbiota-depleted mice

[10]

The metabolism of dietary fiber afforded by gut microbiota can influence the extent of allergic inflammation in the airway in mice

[11]

Lung-skin relationship

The number and/or diversity of gut microbiota at birth is likely to be positively associated with the pathogenesis of skin eczema in human

[2] [3]

About 1% - 2% patients with lung cancer may develop skin metastases

[13]

Elderly women with certain matrix metalloproteinase promotor variants demonstrated a higher susceptibility to skin wrinkling and lung dysfunctions

[19]

About 50% infants who had acute severe bronchiolitis developed dry skin or eczema within 12 months thereafter

[22]