| Baseline & the 1st course | Baseline & the 2nd course | Baseline & the 3rd course | The 1st course & the 2ndcourse | The 1st course & the 3rd course | The 2nd course & the 3rd course |
| |
No improvement | −1.414b | −2.828b | −2.858b | −1.633b | −1.279b | −4.71c | P value | |
0.157 | 0.005 | 0.004 | 0.102 | 0.201 | 0.637 | Z value | ||
Under controlled | −1.857b | −6.607b | −6.532b | −5.427b | −5.105b | −0.200c | P value | |
0.063 | 0.000 | 0.000 | 0.000 | 0.000 | 0.841 | Z value | ||