Time (min)

Treated

Control

P value

15

104.8 ± 37.90

84.54 ± 23.78

0.29

30

55.71 ± 14.39

34.62 ± 9.86

0.012**

45

42.33 ± 7.52

26.11 ± 6.64

0.0019***

60

36.56 ± 3.87

20.18 ± 4.32

0.000016***

75

29.85 ± 4.94

17.45 ± 5.07

0.0011**

90

29.67 ± 5.32

15.13 ± 6.79

0.0014**