| strains | 2005-2006 season | 2006-2007 season | 2007-2008 season | 2008-2009 season | 2009-2010 season | ||||||
| before (95% CI) | 4 weeks after vacc. (95% CI) | before (95% CI) | 4 weeks after vacc. (95% CI) | before (95% CI) | 4 weeks after vacc. (95% CI) | before (95% CI) | 4 weeks after vacc. (95% CI) | before (95% CI) | 4 weeks after vacc. (95% CI) | ||
| H1N1 | seronegativea (n = 32) | 3.13 (−2.90 - 9.16) | 40.6 (23.6 - 57.6) | 0.00 (0.00 - 0.00) | 9.38 (−0.72 - 19.5) | 3.13 (−2.90 - 9.16) | 37.5 (20.7 - 54.3) | 12.5 (1.04 - 24.0) | 34.4 (17.9 - 50.9) | 6.25 (−2.14 - 14.6) | 25.0 (10.0 - 40.0) |
| seropositiveb (n = 79) | 45.6 (34.6 - 56.6) | 92.4 (86.6 - 98.2) | 36.7 (26.1 - 47.3) | 62.0 (51.3 - 72.7) | 7.59 (1.75 - 13.4) | 69.6 (59.5 - 79.7) | 34.2 (23.7 - 44.7) | 55.7 (44.7 - 66.7) | 25.3 (15.7 - 34.9) | 54.4 (43.4 - 65.4) | |
| p-value | 0.000 | 0.000 | - | 0.000 | 0.671 | 0.003 | 0.021 | 0.059 | 0.033 | 0.006 | |
| H3N2 | seronegativea (n = 28) | 0.00 (0.00 - 0.00) | 32.1 (14.8 - 49.4) | 0.00 (0.00 - 0.00) | 21.4 (6.21 - 36.6) | 7.14 (−2.40 - 16.7) | 32.1 (14.8 - 49.4) | 3.57 (−3.30 - 10.4) | 32.1 (14.8 - 49.4) | 7.14 (−2.40 - 16.7) | 28.6 (11.9 - 45.3) |
| seropositiveb (n = 83) | 42.2 (31.6 - 52.8) | 94.0 (88.9 - 99.1) | 34.9 (24.6 - 45.2) | 68.7 (58.7 - 78.7) | 59.0 (48.4 - 69.6) | 88.0 (81.0 - 95.0) | 21.7 (12.8 - 30.6) | 68.7 (58.7 - 78.7) | 38.6 (28.1 - 49.1) | 74.7 (65.3 - 84.1) | |
| p-value | 0.010 | 0.000 | - | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.001 | |
| B | seronegativea (n = 28) | 4.84 (−3.11 - 12.8) | 33.9 (16.4 - 51.4) | 0.00 (0.00 - 0.00) | 6.45 (−2.65 - 15.5) | 0.00 (0.00 - 0.00) | 9.68 (−1.27 - 20.6) | 3.23 (−3.32 - 9.78) | 12.9 (0.48 - 25.3) | 1.61 (−3.05 - 6.27) | 17.7 (3.56 - 31.8) |
| seropositiveb (n = 83) | 40.8 (30.2 - 51.4) | 65.3 (55.1 - 75.5) | 22.4 (13.4 - 31.4) | 38.8 (28.3 - 49.3) | 30.6 (20.7 - 40.5) | 44.9 (34.2 - 55.6) | 30.6 (20.7 - 40.5) | 49.0 (38.2 - 59.8) | 36.7 (26.3 - 47.1) | 61.2 (50.7 - 71.7) | |
| p-value | 0.001 | 0.003 | - | 0.000 | 0.000 | 0.000 | 0.000 | 0.002 | 0.000 | 0.000 | |