Serotype

S. p isolates in PCV7 group (% of participants)a

S. p isolates in Hib group (% of participants) a

Comparison of NP carriage rate at Day 180 between PCV7 and Hib groups

Day 0 n = 1643

Day 180 n = 1475

Day 0 n = 1638

Day 180 n = 1475

Percentage decrease of Nasopharyngeal S. p carriage rate from Day 0 to Day 180 in PCV7 group vs. Hib group (95% CI)

c2 value

P value

4

3 (0.2)

1 (0.1)

2 (0.1)

1 (0.1)

0.0 (−1,497.2, 93.7)

0.00

1.000

6B

32 (2.0)

29 (2.0)

31 (1.8)

36 (2.4)

16.7 (−30.7, 50.3)

0.54

0.380

9V

1 (0.1)

1 (0.1)

0 (0.0)

3 (0.2)

50.0 (−220.1, 96.5)

0.25

0.617

14

28 (1.7)

16 (1.1)

21 (1.2)

29 (2.0)

44.8 (−1.1, 69.9)

3.81

0.051

18C

0 (0.0)

0 (0.0)

1 (0.1)

0 (0.0)

0

/

/

19F

56 (3.4)

45 (3.1)

54 (3.4)

57 (3.9)

21.1 (−15.9, 46.2)

1.33

0.249

23F

24 (1.5)

24 (1.6)

36 (2.2)

20 (1.4)

−14.3 (−116.3, 33.4)

0.37

0.543

Total VT

144 (8.8)

116 (7.9)

145 (8.9)

146 (9.9)

20.2 (−0.3, 37.1)

3.77

0.052

6A

30 (1.8)

28 (1.9)

45 (2.7)

34 (2.3)

17.7 (−35.1, 49.8)

0.59

0.441

Total VT plus 6A

174 (10.6)

144 (9.8)

190 (11.6)

180 (12.2)

20.0 (1.6, 35.0)

4.49

0.034