25

1/M

61

7

Metastatic clear cell

Submandibular and Thyroid Glands

Submandibular gland was excised total thyroidectomy

NR at 6 months

26

1/N/A

N/A

10

Metastatic clear cell

Gastric metastasis

Wedge resection of gastric wall was performed

NR at 18 months

27

1/M

60

19

Metastatic clear cell

Gastric fundus

Wedge resection of the stomach

NR at 12 months

28

1/F

76

17

Metastatic clear cell

Thyroid

Left thyroid lobectomy

No further metastatic disease was identified

29

1/F

80

12

Metastatic clear cell

Thyroid

hemithyroidectomy

NR at 5 years

30

1/M

70

18 months

Metastatic clear cell

Thyroid

Total thyroidectomy

N/A

31

1/F

62

13

Granular cell type RCC

Renal fossa

Resected en bloc

a-interferon

NR at 16 months

32

310

129F/F

181/M

Median age at surgery 61.8

Minimum 5 years after surgery

259 Clear cell

Local recurrence Lung Thorax Bone Brain Lymph nodes Abdomen Pancreas Liver Thyroid gland Adrenal gland Dermis

Surgical and Systemic treatment

Median Follow up after surgery 120 (93 - 149) months

33

30/ N/A

Median age 56

12.4

Clear cell

Lung Kidney Bone Brain Pancreas Lymph node Adrenal gland Liver

16 Surgical treatment 16 chemotherapy 11 Immunotherapy 5 Radiotherapy

NR 9 patients (2011)

Patients >56 years old had worse survival than younger patients

34

1/ N/A

<60

18 months

RCC

13 Cerebral metastasis

Surgical removal and stereotactic Beam irradiation therapy

the patient is in good health at 13 years

35

1/M

66

25

Clear cell

Lung and pleura

Resection and irradiation

Died 26 years after removal of the primary lesion

36

1/F

76

4

Mixed clear and granular cell

Duodenum and colon

Interferon

She is still alive 1 year later

37

1/M

70

17

Metastatic clear cell

Upper right arm Pancreas Thyroid

Total excision Whipple’s operation total thyroidectomy

NR at 54 months

1/F

54

19

Metastatic RCC

Contra lateral kidney Pancreas

right nephrectomy and distal pancreatectomy, Dialysis

NR at 8 months

38

1/M

65

23

Clear cell

Gastric metastasis

wedge resection of the gastric wall.

NR at 2 months

39

1/M

70

26

Metastatic RCC

Rectum

Right lung mediastinum

Interleukin 2 and interferon Snare resection Local radiation

Died after 8 months

40

1/M

78

5

Metastatic clear cell

Gastric metastases

Electrosurgical snare resection

Died after 6 months

41

1/M

68

10

Metastatic clear cell

Gastric and pancreatic metastasis chest, paraaortic lymph-adenopathies, liver

Splenectomy and distal pancreat-ectomy, IL-2, total gastrectomy lymphoadenectomy omentectomy, esophago-jejunostomy, chemotherapy

Died after 3 months

42

1/F

66

2

Metastatic RCC

Stomach, lung, liver

Palliative laparoscopic wedge resection

No symptoms at 8 days

43

1/F

54

9

Metastatic RCC

Duodenum

Radical subtotal gastrectomy

NC at 10 months

Present

1/F

70

10

Metastatic RCC

Mediastinum

Sutant (Sunitinib)

The patient is in good health at 6 months