Ref | Cases/Sex | Age | Interval to metastasis in years | Cell type | Site of metastasis | Treatment | Outcome |
1 | 3/1M/2F | 45 - 64 | 6 - 8 | Clear cell Papillary Clear cell | Right thigh Right atrium & ventricle Bladder | Radical excision Excision TURBT | NR 1 y Died after 6 m NR 3 y |
3 | 1/M | 77 | 10 | Clear cell | Prostate | Sunitinib | Marked regression |
4 | 1/F | 76 | 18 | Clear cell | Brain | Stereotactic radiation | Died after six years |
5 | 1/F | 52 | 10 | Clear cell | Thyroid | Hemithyroidectomy & partial internal jugular vein resection | Had pancreatic metastasis |
6 | 1/M | 83 | 12 | Metastatic RCC | Parotid and Cerebellum | Superficial parotidectomy & stereotactic ablation | Free of disease |
7 | 1/M | 65 | 20 | Metastatic RCC | Falx (meningeal) | Total removal & radiochemo therapy | In good condition at 4 months |
8 | 1/M | 76 | 7 | Clear cell | Perianal lesion | Surgical removal | Has also had a lesion adjacent to the occipital horn of the left lateral ventricle |
9 | 1/F | 65 | 20 | Metastatic RCC | Extra-axial Cerebral | Removal of tumor | Had Lung metastasis |
10 | 1/M | 61 | 19 | Clear cell | Cerebral* & Thyroid | Total excision and Left hemi throidectomy | Fourteen months after surgery no neurological deficit |
11 | 1/M | 63 | 11 | Clear cell | Left Parotid | Left parotidectomy | NR at 4 years |
12 | 1/M | 50 | 3 | Metastatic RCC | Thyroid | Total throidectomy | NR |
13 | 1/F | 56 | 11 | Metastatic RCC | Thyroid and Parotid | Parotidectomy and resection of thyroid metastasis | NR at 2 years |
14 | 1/F | 59 | 10 | Metastatic RCC | Parotid | Superficial parotidectomy | Developed RCC of Left kidney had Radical nephrectomy, now on dialysis NR at 18 months |
15 | 1/M | 83 | 10 | Clear cell | Submaxillary gland | Excision of right submaxillary gland | NR at 1 year |
16 | 1/M | 77 | 15 | Clear cell | Brain | Partial excision then Gamma knife surgery | Right hemiparesis diappeared, Sensory aphasia continued. Rehabilitated |
17 | 1/M | 65 | 19 | Metastatic clear cell | Buccal mucosa | Surgical removal | NR at 6 years |
18 | 1/F | 54 | 16 | Metastatic clear cell | choroid plexus | Stereotactic excision surgery | no neurological deficit at 3 weeks |
19 | 1/F | 80 | 9 | Clear cell | Thyroid | Hemithyroidectomy | Developed Body and head of the pancreas masses. No further treatment was proposed due to patient’s age and comorbidities |
20 | 1/F | 87 | 19 | Metastatic clear cell | Thyroid | Hemithyroidectomy | NR at 28 months |
21 | 1/M | 57 | 4⅟2 | RCC | Renal fossa | Surgical removal | Left lung metastasis removed, 9th right rib lesion on bisphosphonates, with a good response so far. |
22 | 28/M 16/F = 44 | 55 - 71 | Median time 7.7 years | 41 Clear cell 1 Chromophobe 2 Multiple | Lung, bone, pancreas, mediastinum, adrenal, thyroid, lymph nodes, brain | 33 Metastectomy 14 Systemic therapy | Median overall survival 6.1 years |
23 | 29/M 12/M = 41 | 38 - 76 | 63 - 234 months | Mostly clear cell | Lung, liver, bone, brain, retroperitoneal lymph node, adrenal | 22 Metastectomy 26 Systemic therapy | The 5-year cancer-specific survival rate after recurrence was 73.7% |
24 | 1/M | 84 | 45 | Metastatic clear cell | Renal bed, liver, lung |
| Sudden death 8 hours after biopsy |