Genetic variants associated with T2D or glycemic traits | |||||
Localization | Locus name | Chromosome | associated SNP | established loci | Literature |
non- and endodermal | TCF7L2 | 10 | rs4506565, rs7903146, rs12243326 | T2DM | Dupuis et al., 2012; Saxena et al., 2010 |
endodermal | KCNQ1 | 11 | rs2237892, rs231362 | T2DM | Yasuda et al., 2008; Voight et al., 2010 |
endodermal | PROX1 | 1 | rs340874 | T2DM | Dupuis et al., 2012 |
endodermal | HNF1β | 17 | rs757210, rs4430796, rs7501939 | T2DM | Pearson et al., 2007; Winckler et al., 2007; Wang et al., 2014 |
endodermal | KCNJ11 | 11 | rs5219, rs757110 | T2DM | Gloyn et al., 2003 |
endodermal | GCK | 7 | rs1799881, rs6975024, rs4607517, rs3757840 | T2DM | Dupuis et al., 2012; Soranzo et al., 2010; Scott et al., 2012 |
endodermal | FOXA2 | 20 | rs6113722, rs6048205 | T2DM | Scott et al., 2012; Manning et al., 2012 |
endodermal | PDX1 | 13 | rs11619319, rs2293941 | T2DM | Scott et al., 2012; Manning et al., 2012 |