| Treatment time | NO | IL-2 | IL-4 | IL-6 | IL-8 | ||||
| Control group | Treatment group | Control group | Treatment group | Control group | Treatment group | Control group | Treatment group | ||
| pre-treatment | 50 | 79.84 ± 26.4 | 86.00 ± 32.2 | 7.34 ± 2.09 | 6.88 ± 2.31 | 110.83 ± 47.6 | 108.21 ± 44. | 73.11 ± 78.5 | 81.48 ± 94.1 |
| 1 week | 50 | 68.30 ± 25.7 | 78.71 ± 42.3 | 7.53 ± 1.47 | 6.95 ± 5.73 | 91.51 ± 47.8 | 89.71 ± 44.1 | 61.58 ± 78.7 | 67.01 ± 88.4 |
| 4 week | 50 | 56.96 ± 24.2 | 58.26 ± 24.7 | 7.64 ± 3.78 | 7.08 ± 3.65 | 73.21 ± 44.8 | 62.40 ± 42.8 | 57.38 ± 82.1 | 57.56 ± 84.1 |
| 3 months | 50 | 56.18 ± 22.6 | 53.84 ± 27.0 | 7.85 ± 7.69 | 7.58 ± 7.83 | 59.67 ± 44.6 | 42.46 ± 42.1 | 55.83 ± 81.9 | 54.07 ± 84.1 |
| Analysis of variance F |
| 51.883 | 31.543 | 456.226 | 70.142 | ||||
| Analysis of variance P |
| 0.000 | 0.000 | 0.000 | 0.000 | ||||
| Interaction |
| 5.133 | 3.476 | 12.873 | 8.872 | ||||
| Interaction |
| 0.004 | 0.002 | 0.000 | 0.000 | ||||