Characteristics

Fazekas scale

Statistical value

p value

Grade 0

Grade I

Grade II

Grade III

Total number (n)

44

79

44

36

-

-

Age (years; mean ± SD)

61.02 ± 7.9

66.97 ± 11.1

71.75 ± 10.82

76.14 ± 8.1

22.886

0.006

Male/female

25/19

40/39

22/22

10/26

7.558

0.056

Smoking history

43.2%

36.7%

29.5%

25.0%

3.5555

0.314

Hypertension

70.5%

72.2%

79.5%

83.3%

2.656

0.448

Diabetes

31.8%

35.4%

38.6%

33.3%

0.502

0.918

Coronary heart disease

15.9%

4.2%

34.1%

61.1%

17.883

0.000

Stroke history

27.3%

31.6%

52.3%

58.3%

13.080

0.004

Total cholesterol (mmol/L)

4.84 ± 1.35

4.56 ± 1.37

4.08 ± 1.07

4.55 ± 1.21

6.502

0.090

Triglyceride (mmol/L)

2.44 ± 1.99

2.06 ± 0.93

2.00 ± 0.73

1.95 ± 0.85

2.106

0.551

Low-density lipoprotein (mmol/L)

3.50 ± 1.02

3.56 ± 1.12

3.30 ± 0.79

3.60 ± 0.92

2.251

0.522

High-density lipoprotein (mmol/L)

1.33 ± 0.43

1.21 ± 0.42

1.35 ± 0.46

1.28 ± 0.42

3.527

0.317

Apolipoprotein A/B

1.09 ± 0.57

0.93 ± 1.84

0.97 ± 0.13

0.98 ± 0.34

3.606

0.307

Apolipoprotein A1 (mg/L)

0.87 ± 0.44

0.86 ± 0.07

0.87 ± 0.52

0.87 ± 0.59

1.553

0.670

Glycosylated hemoglobin (%)

6.33 ± 1.30

6.42 ± 1.43

6.22 ± 1.15

6.46 ± 1.53

0.902

0.825

Homocysteine (mmol/L)

17.9 ± 8.63

19.5 ± 9.58

23.4 ± 22.8

22.5 ± 16.2

1.389

0.708