CAU (n = 60)

mean (SD)

CM (n = 68)

mean (SD)

t value

P value

PANSS total score

Baseline

44.03 ± 8.74

45.50 ± 10.81

0.84

0.40

1 month

43.13 ± 9.73

43.04 ± 9.38

0.05

0.96

3 month

43.47 ± 11.32

40.95 ± 9.15

1.29

0.20

6 month

40.85 ± 8.81

40.85 ± 9.16

0

1.00

12 month

39.93 ± 9.08

39.89 ± 9.25

0.03

0.98

end point

41.03 ± 9.59

40.93 ± 10.69

0.06

0.95

PSP total score

Baseline

71.25 ± 17.70

67.76 ± 12.91

2.00

0.05

1 month

70.96 ± 17.74

73.09 ± 12.32

0.66

0.51

3 month

72.60 ± 15.39

74.21 ± 11.08

0.64

0.53

6 month

74.81 ± 11.47

74.65 ± 11.21

0.08

0.94

12 month

76.55 ± 11.10

76.44 ± 10.42

0.05

0.96

end point

75.35 ± 10.90

75.54 ± 11.68

0.10

0.92

SF36 total score

Baseline

103.69 ± 13.27

99.50 ± 14.62

1.68

0.10

1 month

104.74 ± 12.47

103.72 ± 13.40

0.43

0.67

3 month

105.73 ± 13.51

103.81 ± 12.77

0.78

0.44

6 month

104.15 ± 15.95

102.65 ± 12.54

0.55

0.58

12 month

104.91 ± 13.90

103.85 ± 12.68

0.41

0.69

end point

102.47 ± 20.24

102.57 ± 13.95

0.04

0.97

SSMI total score

Baseline

35.85 ± 16.13

39.96 ± 15.43

1.47

0.15

1 month

36.23 ± 15.67

36.84 ± 14.34

0.22

0.83

3 month

36.57 ± 15.46

38.09 ± 16.81

0.50

0.62

6 month

35.96 ± 17.16

40.50 ± 16.15

1.42

0.16

12 month

37.43 ± 17.44

38.66 ± 15.59

0.38

0.70

end point

38.02 ± 18.07

39.63 ± 15.57

0.54

0.59

RSESE total score

Baseline

0.91 ± 0.99

1.07 ± 1.27

0.77

0.44

1 month

0.79 ± 1.03

0.85 ± 1.32

0.27

0.79

3 month

1.12 ± 1.63

0.78 ± 1.35

1.20

0.23

6 month

0.73 ± 0.89

0.79 ± 1.22

0.29

0.77

12 month

0.68 ± 0.91

0.94 ± 1.90

0.82

0.41

end point

0.66 ± 0.88

1.00 ± 1.89

1.27

0.21