| Time (min) | Freeze dried Aloe vera gel | Freeze dried Aloe vera gel Loaded PLGA NP | ||
| Rate Constant (min−1) | R2 | Rate Constant (min−1) | R2 | |
| Ph-I: 0 - 240 | 3.6 × 10−3 | 0.88 | 1.2 × 10−3 | 0.93 |
| Ph-II: 240 - 300 | - | - | 6.5 × 10−3 | 0.99 |
| Ph-III: 300 - 540 | - | - | 1.5 × 10−3 | 0.97 |