Ovariectomized rats’ femur treated with fibrates and statins. Assessment of pore-size distribution by 1H-NMR relaxometry

In-vitro

Şipoş, R.S., Fechete, R., Chelcea, R.I., Moldovan, D., Pap, Z., Pávai, Z., Demco, D.E.

2015

Romania

Fenofibrate

Neutral

The PPAR agonist fenofibrate improves the musculoskeletal effects of exercise in ovariectomized rats

In vitro

Mosti, M.P., Ericsson, M., Erben, R.G., Schüler, C., Syversen, U., Stunes, A.K.

2016

Norway

Fenofibrate

Positive

Fenofibrate decreases the bone quality by down regulating Runx2 in high-fat-diet induced Type 2 diabetes mellitus mouse model

In vitro

Shi, T., Lu, K., Shen, S., Tang, Q., Zhang, K., Zhu, X., Shi, Y., Liu, X., Teng, H., Li, C., Xue, B., Jiang, Q.

2017

China

Fenofibrate

Negative

Fenofibrate induces PPARα and BMP2 expression to stimulate osteoblast differentiation

In vitro

Kim, Y.H., Jang, W.G., Oh, S.H., Kim, J.W., Lee, M.N., Song, J.H., Yang, J.W., Zang, Y., Koh, J.T.

2019

Republic of Korea

Fenofibrate

Positive