| Work title | Type of study | Authors | Year | Place | Drug | Effect |
| PPAR agonists modulate human osteoclast formation and activity in vitro | In vitro | Chan, B.Y., Gartland, A., Wilson, P.J., Buckley, K.A., Dillon, J.P., Fraser, W.D., Gallagher, J.A. | 2006 | U.K | Fenofibrate | Neutral |
| The peroxisome proliferator activator receptor alpha/delta agonists linoleic acid and bezafibrate upregulate osteoblast differentiation and induce periosteal bone formation in vivo | In-vitro and In-vivo | Still, K., Grabowski, P., Mackie, I., Perry, M., Bishop, N. | 2008 | U.K | Fenofibrate | Positive |
| Bezafibrate prevents palmitate-induced apoptosis in osteoblastic MC3T3-E1 cells through the NF-κB signaling pathway | In-vitro | Zhong, X., Xiu, L., Wei, G., Pan, T., Liu, Y., Su, L., Li, Y., Xiao, H. | 2011 | China | Bezafibrate | Positive |
| Bezafibrate enhances proliferation and differentiation of osteoblastic MC3T3-E1 cells via AMPK and eNOS activation | In-vitro | Zhong, X., Xiu, L.L., Wei, G.H., Liu, Y.Y., Su, L., Cao, X.P., Li, Y.B., Xiao, H.P. | 2011 | China | Bezafibrate | Positive |
| The peroxisome proliferator-activated receptor (PPAR) alpha agonist fenofibrate maintains bone mass, while the PPAR gamma agonist pioglitazone exaggerates bone loss, in ovariectomized rats | In-vitro | Stunes, A.K., Westbroek, I., Gustafsson, B.I., Fossmark, R., Waarsing, J.H., Eriksen, E.F., Petzold, C., Reseland, J.E., Syversen, U. | 2011 | Norway | Fenofibrate | Negative |
| Combination treatment with pioglitazone and fenofibrate attenuates pioglitazone-mediated acceleration of bone loss in ovariectomized rats | In-vitro | Samadfam, R., Awori, M., Bénardeau, A., Bauss, F., Sebokova, E., Wright, M., Smith, S.Y. | 2012 | Canada | Fenofibrate | Positive |
| PPAR agonists stimulate adipogenesis at the expense of osteoblast differentiation while inhibiting osteoclast formation and activity | In-vitro | Jessal, J. P., Oliver, R. B., Timothy, R. A. | 2014 | U.K. | Fenofibrate | Neutral |
| Effects of pioglitazone and fenofibrate co-administration on bone biomechanics and histomorphometry in ovariectomized rats | Pre-Clinical Trial | Susan, Y. S., Rana, S., Luc, C. | 2015 | Canada | Fenofibrate | Negative |