Rosuvastatin 1.2 mg in Situ Gel Combined it 1:1 Mixture of autologous platelet-rich fibrin and porus-hydroxyappatite bone graft in surgical treatment of mandibular degree ii furcation defects: a randomized clinical control trial

Clinical Trial

Pradeep, A. R., Karvekar, S., Nagpal, K.

2016

India

Rosuvastatin

Positive

Rosuvastatin Regulates Odontoblast Differentiation by Suppressing NF-jB Activation in an Inflammatory Environment

Pre-Clinical Trial

Feng, X., Wang, C., Gu, Z.

2019

China

Rosuvastatin

Positive

Diagnosis of osteoporosis in statin-treated patients is dose-dependent

Clinical Trial

1) Leutner, M.,

2) Matzhold, C.,

3) Bellach, L.

2019

Austria

Lovastatin, Sinvastatin, Pravastatin and Rosuvastatin

Dosis-dependent could be positive or not

Atorvastatin promotes bone formation in aged apoE–/– mice through the Sirt1–Runx2 axis

Pre-Clinical Trial

Hong, W., Wei, Z., Qiu, Z.

2020

China

Atorvastatin

Positive

Comparison the effects of chitosan and hyaluronic acid-based thermally sensitive hydrogels containing rosuvastatin on human osteoblast-like MG-63 cells

Pre-Clinical Trial

In-vitro

Akbari, V., Rezazadeh, M., & Ebrahimi, Z.

2020

Iran

Rosuvastatin

Positive

Evaluation of the effects of locally applied rosuvastatin on bone formation in a three dimensional reconstruction rabbit xenograft model

Pre-Clinical Trial

Özer, T., Aktaş, A., Avağ, C.

2021

Turkey

Rosuvastatin

Positive

Peri-implant marginal bone loss and systemic statin use: A retrospective cohort pilot study

Clinical Trial

Bahrami-Hessari, B., & Jansson, L.

2022

Sweden

Negative

Comparative evaluation of autogenous bone graft and autologous platelet—Rich fibrin with and without 1.2 mg in situ rosuvastatin gel in the surgical treatment of intrabony defect in chronic periodontitis patients

Clinical Trial

Gautam, K., Kapoor, A., Mathur, S.

2022

India

Rosuvastatin

Positive