| Rosuvastatin Promotes Osteoblast Differentiation and Regulates SLCO1A1 Transporter Gene Expression in MC3T3-E1 Cells | Pre-Clinical Trial | Monjo, M., Rubert, M., Ellingsen, J. E. | 2010 | Spain | Rosuvastatin | Positive |
| Bisphosphonate- and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2 | Pre-Clinical Trial | Tsubaki, M., Satou, T., Itoh, T. | 2012 | Japan | Positive | |
| Rosuvastatin inhibits spontaneous and IL-1-induced interleukin-6 production from human cultured osteoblastic cells | Pre-Clinical Trial and Clinical Trial | Lazzerini, P. E., Capperucci, C., Spreafico, A. | 2013 | Italy | Rosuvastatin | Positive |
| Discontinuation of simvastatin leads to a rebound phenomenon and results in immediate peri-implant bone loss | Pre-Clinical Trial | Li, X., Wu, F., Zhang, Y. | 2016 | Japan, China | Simvastatin | Negative |
| The effect of atorvastatin, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor (HMG-CoA), on the prevention of osteoporosis in ovariectomized rabbits | Pre-Clinical Trial | Zhou, H., Xie, Y., Baloch, Z. | 2016 | China | Atorvastatin | Positive |
| Anti-inflammatory effect of rosuvastatin decreases alveolar bone loss in experimental periodontitis | Pre-Clinical Trial | Kırzıoğlu, F. Y., Tözüm Bulut, M., Doğan, B. | 2016 | Turkey | Rosuvastatin | Positive |
| 1.2% Rosuvastatin versus 1.2% Atorvastatin Gel local drug delivery and re-delivery in treatment of intrabony defects in chronic periodontitis: A randomized placebo controlled clinical trial | Clinical Trial | Pradeep, A. R., Garg, V., Kanoriya, D. | 2016 | India | Rosuvastatin and Atorvastatin | Positive |