Work title

Type of study

Authors

Year

Place

Drug

Effect

Effect of pravastatin on frequency of fracture in the LIPID study: secondary analysis of a randomised controlled trial

Clinical Trial

Reid, I. R., Hague, W., Emberson, J.

2001

New Zealand

Pravastatin

Neutral

Statin given perorally to adult rats increases cancellous bone mass and compressive strength

Pre-Clinical Trial

IN., Dalstra, M., Andreassen, T. T.

2001

Denmark

Simvastatin

Positive

The effect of atorvastatin on markers of bone turnover in patients with type 2 diabetes

Clinical Trial

Braatvedt, G. D., Bagg, W., Gamble, G.

2004

New Zealand

Atorvastatin

Neutral

Simvastatin treatment partially prevents ovariectomy-induced bone loss while increasing cortical bone formation

Pre-Clinical Trial

Oxlund, H., & Andreassen, T. T

2004

Denmark

Simvastatin

Positive

Effects of Atorvastatin on Bone in Postmenopausal Women with Dyslipidemia: A Double-Blind, Placebo-Controlled, Dose-Ranging Trial

Clinical Trial

Bone, H. G., Kiel, D. P., Lindsay, R. S.

2007

EE.UU

Atorvastatin

Neutral

A Comparison between the Effects of Hydrophobic and Hydrophilic Statins on Osteoclast Function In Vitro and Ovariectomy-Induced Bone Loss In Vivo

Pre-Clinical Trial

Hughes, A., Rogers, M. J., Idris, A. I.

2007

U.K

Rosuvastatin, Pravastatin, Cerivastatin and Sinvastatin

Neutral

Statins attenuate polymethylmethacrylate-mediated monocyte activation

Pre-Clinical Trial In-vitro

Laing, A. J., Dillon, J. P., Mulhall, K. J.

2008

Ireland

Cerivastatin

Positive

Effects of statins vs. non-statin lipid-lowering therapy on bone formation and bone mineral density biomarkers in patients with hiperlipidemia

Clinical Trial

Chuengsamarn, S., Rattanamongkoulgul, S., Suwanwalaikorn, S.

2010

Thailand

Simvastatin, Gemfibrozil

Positive

Simvastatin promotes osteoblast viability and differentiation via Ras/Smad/Erk/BMP-2 signaling pathway

Pre-Clinical Trial

Chen, P. Y., Sun, J. S., Tsuang, Y. H.

2010

Taiwan

Simvastatin

Positive