Method

Definition principle

Advantage

Disadvantage

Clinical application

DWI

Detection of diffusion of water molecules in living tissue

No contrast agent;

High sensitivity;

Easy to operate;

Low image resolution;

Low specificity

Most basic and

widely used

DCE-MRI

Evaluation of breast tumor angiogenesis

High sensitivity, accuracy and specificity;

Quantitative judgment

Complex to operate;

Most basic and

widely used

MRS

Study changes in tumor metabolite content

analyze metabolites;

Quantitative assessment of lipid metabolism

Longer imaging time;

Quantification of choline concentration is difficult to standardize

Frequently used

PWI

Reflecting microvascular distribution and blood perfusion status of breast tissue

Reflect microvascular distribution and blood perfusion status;

Higher diagnostic specificity

Low sensitivity;

Heterogeneity in blood perfusion;

Less used

PET/MRI

A system of functional imaging and structural imaging at the molecular level

Functional imaging at the molecular level;

High sensitivity,

accuracy and specificity;

Complex to operate;

Less technicians and diagnosticians;

Radioactivity expensive

Rarely used

Mammography imaging and imaging genomics

Studying the link between breast cancer genomic features and imaging features

Create a high-dimensional data set;

Using image features to reflect gene activity

Too small sample size;

Clinically practical is not strong

Used only for

academic research