| Name | Use concentration (%) | EC50/mg∙L−1 | Toxicity classification |
| RH-225 | 5.0 | >30,000 | Non-toxic |
| KCOOH | 5.0 | >100,000 | Non-toxic |
| G-SPH | 4.0 | >30,000 | Non-toxic |
| CQA-10 | 3.0 | >100,000 | Non-toxic |
| ZX-1 | 1.5 | >100,000 | Non-toxic |
| Formula | Drilling fluid system | >30,000 | Non-toxic |