Outcome | Group R | Group S | |
Rapid EN advancement | Slow EN advancement | P value | |
n=41 | n=24 | ||
All-cause mortality | |||
In EICU, n (%) | 0 (0) | 0 (0) | 1.000 |
In hospital, n (%) | 3 (7) | 0 (0) | 0.244 |
Length of stay | |||
ICU-free days, days; median (IQR) | 19.0 (13.5 - 22.0) | 20.5 (15.3 - 23.0) | 0.309 |
Length of hospital stay, days; median (IQR) | 38.3 (29.1 - 54.1) | 50.4 (35.7 - 61.2) | 0.128 |
Mechanical ventilation | |||
Mechanical ventilation-free days, days; median (IQR) | 18.0 (0.0 - 22.0) | 21.0 (16.3 - 24.8) | 0.046 |
Requirement for mechanical ventilation at hospital discharge, n (%) | 12 (29) | 2 (8) | 0.030 |
Tracheostomy, n (%) | |||
In EICU | 18 (44) | 12 (50) | 0.448 |
In hospital | 26 (63) | 17 (71) | 0.422 |
Antibiotic-free days, days; median (IQR) | 15.0 (8.5 - 19.0) | 12.5 (8.0 - 18.8) | 0.410 |
Highest CRP, mg/dl; median (IQR) | 16.0 (9.6 - 22.9) | 16.2 (8.3 - 21.6) | 0.703 |
Pneumonia | |||
Clinical diagnosis of pneumonia, n (%) | 16 (39) | 9 (38) | 0.559 |
Development of VAP, n (%) | 1 (2) | 0 (0) | 0.631 |
Liver and kidney dysfunction | |||
Liver dysfunction (serum bilirubin > 1.2 mg/dl), n (%) | 9 (22) | 6 (25) | 0.503 |
Renal dysfunction (serum creatinine > 1.2 mg/dl) or requirement for RRT, n (%) | 16 (39) | 4 (17) | 0.052 |
Glycemic control | |||
Hypoglycemia (<70 mg/dl) free days, days; median (IQR) | 28.0 (26.5 - 28.0) | 28.0 (27.0 - 28.0) | 0.539 |
Received insulin administration, n (%) | |||
First week in EICU | 19 (46) | 6 (25) | 0.073 |
During 28 days after EICU admission | 22 (54) | 8 (33) | 0.092 |
Average insulin daily dose (units) | |||
First week in EICU | 7.8 (2.7 - 16.8) | 4.8 (1.6 - 26.3) | 0.775 |
During 28 days after EICU admission | 2.5 (0.6 - 11.0) | 1.2 (0.4 - 20.6) | 0.386 |
Electrolytes | |||
Hypophosphatemia (<2.7 mg/dl), n (%) | |||
First week in EICU | 18 (44) | 8 (33) | 0.193 |
During 28 days after EICU admission | 22 (54) | 8 (33) | 0.400 |