| Baseline |
| 8th week |
| p | ||||
| Mean | Std. Deviation |
| Mean | Std. Deviation |
| |||
| Age | 65.4 | 10.3 |
|
| ||||
| Disease duration (years) | 10.4 | 6.1 |
|
| ||||
| Daily levodopa (mg) | 553.2 | 228.7 |
|
| ||||
| Frequency of the levodopa consumption | 4.7 | 1.5 |
|
| ||||
| Levodopa equivalent dose (mg) | 811.2 | 307.5 |
|
| ||||
| Unified Parkinson's disease Rating scale |
|
| ||||||
| Total | 32.1 | 24.2 |
| 28.5 | 21.4 |
| 0.030* | |
| Part II | 8.3 | 7.2 |
| 6.9 | 5.7 |
| 0.015* | |
| Part III | 19.4 | 16.9 |
| 17.2 | 15.3 |
| 0.107 | |
| Part IV | 3.9 | 1.9 |
| 3.7 | 2.6 |
| 0.897 | |
| On time (hours) | 12.0 | 3.4 |
| 14.0 | 3.4 |
| 0.008** | |
| Off time (hours) | 5.3 | 3.1 |
| 3.1 | 2.8 |
| 0.007** | |
| Epworth sleepiness scale | 7.0 | 5.6 |
| 6.1 | 5.3 |
| 0.458 | |