| Group Variables | No. of Studies | Prevalence of EGFR Positivity % (95% CI) | Tests of Heterogeneity | ||
| Q | p-value | I2 (%) | |||
| Overall NSCLC | 34 | 25.9 (22.7 to 29.3) | 430.6 | <0.0001 | 92.3 |
| Gender | |||||
| Male | 21 | 24.3 (19.3 to 29.7) | 252.5 | <0.0001 | 92.1 |
| Female | 21 | 42.8 (36.9 to 46.9) | 82.3 | <0.0001 | 75.7 |
| Smoking Status | |||||
| Smokers | 17 | 21.2 (16.3 to 26.6) | 106.4 | <0.0001 | 85.0 |
| Non-smokers | 17 | 39.8 (35.5 to 44.3) | 71.6 | <0.0001 | 77.6 |
| Histology | |||||
| ADC | 34 | 39.5 (32.1 to 47.1) | 1442.2 | <0.0001 | 97.7 |
| Exon Subtype | |||||
| Exon 19 | 23 | 61.9 (57.6 to 66.2) | 53.8 | 0.0002 | 59.1 |
| Exon 21 | 23 | 29.2 (25.5 to 33.1) | 47.1 | 0.0015 | 53.2 |