Variables

OR (95% CI)

I² (%)

Statistical power

Prior probability of 0.001

Prior probability of 0.001

OR = 1.2

OR = 1.5

OR = 1.2

OR = 1.5

TP53 Arg72Pro

Overall

AP vs. AA

1.17 (1.04 - 1.31)

66.2

0.908

1.000

0.970

0.967

0.999

PP + AP vs. AA

1.17 (1.04 - 1.32)

73.8

0.908

1.000

0.970

0.967

0.999

P vs. A

1.09 (1.00 - 1.18)

78.0

0.999

1.000

0.985

0.985

1.000

Asian

AP vs. AA

1.13 (1.02 - 1.25)

46.2

0.878

1.000

0.952

0.946

0.999

PP + AP vs. AA

1.16 (1.03 - 1.30)

64.8

0.720

1.000

0.937

0.914

0.997

P vs. A

1.10 (1.00 - 1.20)

75.9

0.975

1.000

0.970

0.969

0.999

HB

AP vs. AA

1.12 (1.00 - 1.25)

51.0

0.891

1.000

0.980

0.977

0.999

Healthy

AP vs. AA

1.13 (1.01 - 1.28)

51.6

0.828

1.000

0.985

0.982

0.999

PP + AP vs. AA

1.15 (1.01 - 1.30)

62.9

0.752

1.000

0.971

0.962

0.999

P vs. A

1.10 (1.00 - 1.21)

73.6

0.963

1.000

0.981

0.980

0.999

Gendering

Female

PP + AP vs. AA

1.48 (1.04 - 2.08)

0.0

0.114

0.531

0.995

0.978

0.997

P vs. A

1.32 (1.03 - 1.70)

17.3

0.230

0.839

0.993

0.974

0.998

HWE and Quality score > 12

Non-gastric cancer

PP vs. AP + AA

1.33 (1.07 - 1.64)

0.0

0.168

0.870

0.978

0.898

0.994