Study | N | Chemo × Cycles | Thoracic Radiotherapy | PCI | MST (Months) | p-value | ||
Concurrent or Sequential | Total Dose (Gy) | Once or Twice Daily | ||||||
Turrisi AT III, et al., 1999 [7] | 206 | PE × 4 | early C | 45 | O; 25 × 1.8 | Yes | 19.0 | 0.04 |
211 | T; 30 × 1.5 | 23.0 | ||||||
Takada M, et al., 2002 [8] | 114 | PE × 4 | Sequential | 45 | T; 30 × 1.5 | Yes | 19.7 | 0.02 |
114 | early C | 27.2 | ||||||
Faivre-Finn C, et al., 2017 [9] | 273 | PE × 4-6 | early C | 66 | O; 33 × 2.0 | Yes | 25.0 | 0.14 |
274 | 45 | T; 30 × 1.5 | 30.0 | |||||
Skarlos DV, et al., 2001 [10] | 42 | CE × 6 | early C | 45 | T; 30 × 1.5 | Yes | 17.5 | NS |
39 | late C | 17.0 |