| HIPEC | NIPS |
Timing | Intraoperative | Neoadjuvant |
Intraperitoneal Chemotherapy | Cisplatin or Mitomycin-C or Oxaliplatin or Doxorubicin | Paclitaxel or Docetaxel |
Intraabdominal Temperature | 40˚C - 45˚C | Body Temperature |
Systemic Chemotherapy | Yes or No | Yes |
Morbidity | High-Intermediate | Intermediate |
Mortality | Yes | No |
Expertise | High | Low |
Efficacy | High | High |
Level of Evidence | Intermediate | Low |
Capital Investment | High | Low |
Health hazard | Potential | Minimal |