Treatment | Dose (mg/kg b.w.) | Increase in Paw edema volume (mL) | Inhibition (%) | ||||
1 H | 3 H | 5 H | 1 H | 3 H | 5 H | ||
Control | - | 0.40 ± 0.03 | 0.50 ± 0.03 | 0.60 ± 0.04 | - | - | - |
AAS | 100 | 0.17 ± 0.00a | 0.17 ± 0.02a | 0.08 ± 0.01a | 57.7 ± 0.5 | 64.8 ± 4.0 | 87.0 ± 2.3 |
DEC | 200 | 0.30 ± 0.03b | 0.26 ± 0.01b | 0.22 ± 0.02b | 26.4 ± 2.3b | 47.7 ± 1.7b | 63.9 ± 3.8b |
DEC | 400 | 0.26 ± 0.02b | 0.21 ± 0.01b | 0.14 ± 0.02b | 36.4 ± 2.5d | 58.5 ± 1.9d | 76.0 ± 3.4d |
DEC | 600 | 0.23 ± 0.03a | 0.14 ± 0.03a | 0.10 ± 0.03a | 42.3 ± 3.9 $ | 75.9 ± 3.2$ | 82.8 ± 2.8$ |
MAC | 200 | 0.36 ± 0.02d | 0.33 ± 0.01d | 0.33 ± 0.03d | 9.3 ± 3.9a | 33.7 ± 1.6a | 45.0 ± 4.4a |
MAC | 400 | 0.25 ± 0.03a | 0.20 ± 0.05a | 0.12 ± 0.01a | 33.7 ± 3.1d | 54.3 ± 1.9d | 79.4 ± 2.5d |
MAC | 600 | 0.20 ± 0.01a | 0.15 ± 0.01a | 0.1 ± 0.02a | 49.8 ± 3.6$ | 69.4 ± 1.4$ | 84.1 ± 2.8$ |