Groups

Dose (mg/kg)

Before diabetes induction (0 day)

Blood Glucose Level (mg/dl) (After diabetes induction (14^th day)

14^th Day

28^th Day

Control

Vehicle

59.50 ± 2.09

65.33 ± 1.76

68.33 ± 2.03

60.50 ± 1.87

Diabetic control

Vehicle

81.78 ± 2.01^a

251.50 ± 1.29^a

272.00 ± 3.13^a

304.50 ± 2.04^a

HAFE

100

70.50 ± 1.89

264.13 ± 1.70^a

157.00 ± 3.22^b

92.67 ± 2.41^b

HAFE

200

62.50 ± 1.19

242.18 ± 5.02^a

155.17 ± 4.54^b

85.33 ± 3.51^b,c

HALE

100

71.50 ± 2.09

264.13 ± 1.70^a

173.00 ± 3.22^b

96.17 ± 1.42^b

HALE

200

63.50 ± 1.02

257.33 ± 1.04^a

163.17 ± 4.54^b

88.14 ± 3.51^b,c

Glibenclamide (Standard)

5

61.00 ± 2.12

252.67 ± 8.71^a

142.83 ± 3.22^b

73.16 ± 1.57^b,c