Groups/Days	T0	T1	T2	T3
S group
IL-6	20 ± 10.3	400.2 ± 70.5^a	262.9 ± 61.7^ab	157.8 ± 40.7^abc
CRP	6.8 ± 1.7	95.6 ± 20.2^a	113.4 ± 25.8^ab	148.4 ± 32.4^abc
TNF-α	0.39 ± 0.45	0.46 ± 0.59	0.42 ± 0.45	0.42 ± 0.46
SIRS score	0.14 ± 0.35	2.1 ± 1.0^a	1.2 ± 1.0^a	0.57 ± 0.69^abc
P group
IL-6	22.0 ± 8.1	278.2 ± 64.8^a	188.5 ± 51.6^ab	121.0 ± 35.6^abc
CRP	6.6 ± 1.6	86.8 ± 13.9^a	105.1 ± 15.4^ab	136.4 ± 19.8^abc
TNF-α	0.47 ± 0.43	0.53 ± 0.38	0.43 ± 0.32	0.39 ± 0.34
SIRS score	0.14 ± 0.35	1.6 ± 0.84^a	0.67 ± 0.79^a	0.28 ± 0.51^b
D group
IL-6	21.6 ± 8.8	239.4 ± 56.2^a	163.4 ± 31.1^ab	110.8 ± 25.7^abc
CRP	7.1 ± 2.2	77.9 ± 18.8^a	91.9 ± 18.5^ab	124.4 ± 17.1^abc
TNF-α	0.41 ± 0.43	0.43 ± 0.39	0.43 ± 0.32	0.45 ± 0.35
SIRS score	0.13 ± 0.34	1.6 ± 0.78^a	0.74 ± 0.92^a	0.24 ± 0.54^bc
P + D group
IL-6	18.9 ± 9.2	192.1 ± 22.7^a	138.2 ± 18.7^ab	105.5 ± 13.7^abc
CRP	7.3 ± 1.9	52.0 ± 14.5^a	74.3 ± 17.1^ab	113.4 ± 21.5^abc
TNF-α	0.43 ± 0.48	0.50 ± 0.49	0.49 ± 0.38	0.51 ± 0.35
SIRS score	0.17 ± 0.38	1.4 ± 0.73^a	0.58 ± 0.73	0.22 ± 0.42^b