Study Group

Time (mins) to Pharmacokinetic and Pharmacodynamic Endpoints

Threshold plasma

Concentration^a

Time to 50%

Responders^a

Time to 5-point

Change in DSST^b

Zolpidem LS 10 mg

7.0

11.0

4.8

Zolpidem LS 5 mg

10.5

13.5

8.0

AMBIEN 10 mg

15.0

18.5

14.0

AMBIEN 5 mg

17.2

22.2

16.2