Parameter

C-S rats n = 8 after 2 months of vehicle

C-CBL rats n = 6 after 2 months of CBL

D-S rats n = 11 after 2 months of vehicle

D-CBL rats n = 15 after 2 months of CBL

Body weight (g)

460 ± 14.82

471 ± 9.21

268 ± 11.79*

254 ± 10.12*

Heart weight (g)

1.45 ± 0.11

1.5 ± 0.10

1.18 ± 0.07*

1.16 ± 0.057*

Blood glucose mg/dl

151 ± 5.86

156 ± 5.71

466 ± 31.21*

461 ± 26.19*

Relation heart wt/body wt (%)

0.315

0.318

0.430*

0.450*

P-P interval (msec)

161 ± 0.95

164 ± 1.43

220 ± 0.68*

192 ± 0.82*¨

P-P interval (msec) standard deviation

18 ± 0.93

14 ± 1.06

14 ± 0.71

15 ± 0.68

Hear rate (beat/min)

362 ± 12.95

367 ± 8.44

272 ± 7.99*

306 ± 6.51*¨

SABP (mmHg)

138 ± 3.14

140 ± 2.88¨

156 ± 7.09*

162 ± 6.91*

DABP (mmHg).

88 ± 2.5

93 ± 3.33

104 ± 2.74*

96 ± 3.38*