Groups | Body weight in Grams | ||||
Dose interval | |||||
| 0 day | 7 day | 14 day | 21 day | 28 day |
Normal control | 115.4 ± 1.9 | 126.6 ± 1.2 | 139.3 ± 2.0 | 153.7 ± 2.7 | 178.34 ± 2.5 |
Diabetic controla | 116.7 ± 1.3 | 122.7 ± 0.89 | 115.6 ± 1.4 | 113 ± 2.4 | 109.67 ± 2.8** |
Leaf extract 200 mg/kg BWb | 117.3 ± 0.89 | 124 ± 1.6 | 133 ± 2.7*** | 143.4 ± 2.8*** | 155 ± 1.6*** |
Leaf extract 350 mg/kg BWb | 118.4 ± 1.5 | 128 ± 1.6 | 140 ± 1.8*** | 152 ± 1.1*** | 165.34 ± 2.2*** |
Metformin 850mg/70 kg BWb | 120. ± .34 | 131.4 ± 1.9 | 139.7 ± 2.2*** | 153 ± 2.7*** | 170.34 ± 2.9*** |
Metformin 425 mg/70 kg BW + Leaf extract 250 mg/kg BWb | 118.4 ± 0.89 | 129 ± 0.6 | 138 ± 1.1*** | 148.3 ± 1.9*** | 162.34 ± 2.0*** |