Groups

Total

cholesterol

Triglyceride

Low density

lipoprotein

High density

lipoprotein

Left ventricular

hypertrophy

Normal control

153.34 ± 2.2

123.34 ± 2.7

96.33 ± 0.89

42.33 ± 2.2

0.0032

Diabetic controla

213.34 ± 1.5***

238.34 ± 4.4***

145.34 ± 3.6***

32.34 ± 2.9*

0.0043*

Leaf extract 200 mg/kg BWb

167.67 ± 1.5***

169.34 ± 4.3***

91 ± 1.2***

38.33 ± 1.8**

0.0027***

Leaf extract 350 mg/kg BWb

154.67 ± 0.9***

140.67 ± 3.9***

78.67 ± 1.3***

55.66 ± 1.5***

0.0033***

Metformin 850 mg/70 kg BWb

158.34 ± 1.8***

149.34 ± 2.4***

84.66 ± 2.4***

57 ± 3.0***

0.0029***

Metformin 425 mg/70 kg BW + Leaf extract 250 mg/kg BWb

175.67 ± 2.0***

150.34 ± 5.3***

99.33 ± 2.8***

49 ± 2.7***

0.0028***