Groups

Normal

control (NC)

Diabetic control (DC)a

Leaf extract 200 mg/kg BWb

Leaf extract 350 mg/kg BW

Metformin 850 mg/70 kg BWb

Metformin 425 mg/70 kg BW + Leaf extract 250 mg/kg BWb

BG level before four weeks treatment

5.2 ± 0.058

24 ± 0.26

26.7 ± 0.39

23.5 ± 1.0

22.6 ± 2.0

23.7 ± 2.0

BG level after four weeks treatment

5.7 ± 0.2

25.3 ± 0.78***

15.4 ± 1.5***

6.9 ± 0.57***

7.3 ± 0.29***

9.2 ± 0.57***