GABRD

Gamma-aminobutyric acid type A receptor subunit delta

GOTERM_BP_DIRECT

chloride transport, signal transduction, chemical synaptic transmission, ion transmembrane transport, regulation of membrane potential, neurological system process, excitatory postsynaptic potential, chloride transmembrane transport

GOTERM_CC_DIRECT

plasma membrane, integral component of plasma membrane, integral component of membrane, axon, dendrite, chloride channel complex, neuron projection, neuronal cell body, synapse, postsynaptic membrane, GABA-ergic synapse, integral component of postsynaptic membrane, GABA-A receptor complex

GOTERM_MF_DIRECT

GABA-A receptor activity, ion channel activity, extracellular ligand-gated ion channel activity, chloride channel activity, protein binding, neurotransmitter receptor activity, transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential

INTERPRO

Gamma-aminobutyric acid A receptor, Neurotransmitter-gated ion-channel transmembrane domain, Neurotransmitter-gated ion-channel, Neurotransmitter-gated ion-channel ligand-binding, Gamma-aminobutyric-acid A receptor delta subunit, Neurotransmitter-gated ion-channel, conserved site

KEGG_PATHWAY

Neuroactive ligand-receptor interaction, Retrograde endocannabinoid signaling, GABAergic synapse, Morphine addiction, Nicotine addiction

OMIM_DISEASE

Epilepsy, idiopathic generalized, 10, Epilepsy, juvenile myoclonic, susceptibility to, Generalized epilepsy with febrile seizures plus, type 5, susceptibility to

UP_KW_BIOLOGICAL_PROCESS

Ion transport, Transport

UP_KW_CELLULAR_COMPONENT

Membrane, Postsynaptic cell membrane, Synapse, Cell membrane

UP_KW_DISEASE

Disease variant, Epilepsy

UP_KW_DOMAIN

Signal, Transmembrane, Transmembrane helix

UP_KW_LIGAND

Chloride

UP_KW_MOLECULAR_FUNCTION

Ion channel, Receptor, Chloride channel

UP_KW_PTM

Glycoprotein, Phosphoprotein, Disulfide bond

HRH1

histamine receptor H1

GOTERM_BP_DIRECT

inflammatory response, G-protein coupled receptor signaling pathway, G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger, phospholipase C-activating G-protein coupled receptor signaling pathway, chemical synaptic transmission, memory, visual learning, positive regulation of inositol trisphosphate biosynthetic process, regulation of vascular permeability, positive regulation of vasoconstriction, inositol phosphate-mediated signaling, regulation of synaptic plasticity, eosinophil chemotaxis, cellular response to histamine, G-protein coupled serotonin receptor signaling pathway

GOTERM_CC_DIRECT

cytosol, plasma membrane, integral component of plasma membrane, dendrite, synapse

GOTERM_MF_DIRECT

G-protein coupled receptor activity, histamine receptor activity, G-protein coupled serotonin receptor activity, neurotransmitter receptor activity

INTERPRO

G protein-coupled receptor, rhodopsin-like, Histamine H1 receptor, GPCR, rhodopsin-like, 7TM

KEGG_PATHWAY

Calcium signaling pathway, Neuroactive ligand-receptor interaction, Inflammatory mediator regulation of TRP channels

SMART

SM01381

UP_KW_CELLULAR_COMPONENT

Membrane, Cell membrane

UP_KW_DOMAIN

Transmembrane, Transmembrane helix

UP_KW_MOLECULAR_FUNCTION

G-protein coupled receptor, Receptor, Transducer

UP_KW_PTM

Glycoprotein, Phosphoprotein, Disulfide bond