Obesity Not obese Obese |
48 33 |
59.3 40.7 |
ECOG PS 0, I II |
5 76 |
6.2 93.8 |
Prior trastuzumab Yes No |
17 64 |
21.0 79.0 |
Prior locoregional radiotherapy to left breast Yes No |
21 60 |
25.9 74.1 |
Prior anthracycline-based regimen Doxorubicin-based Epirubicin-based |
32 49 |
39.5 60.5 |
Cumulative dose of priordoxorubicin Mean ± SD |
253.1 ± 25.2 | |
Cumulative dose of prior epirubicin Mean ± SD |
588.0 ± 97.3 | |
Number of PLD cycles Mean (Range) |
7.57 (2 - 24) | |
Cumulative dose of PLD (mg/m2) Mean ± SD Range |
378.4 ± 250.2 100 - 1200 | |
High PLD cumulative dose (≥400 mg/m2) Yes No |
31 50 |
38.3 61.7 |