Study ID

Significant factors

Odds

Ratio

95% CI

p-value

Pre-operative phase

Angarita 2011 [26]

Active skin disorders

36.39

7.76 - 173.45

<0.001

Chung 2015 [30]

Hypertension

1.82

1.41 - 2.33

<0.001

Pulmonary comorbidity

4.29

1.43 - 12.82

0.009

Olsen 2016 [57]

Depression

1.62

1.17 - 2.24

0.004

Obesity

1.85

1.35 - 2.54

<0.001

Liver disease

4.07

1.71 - 9.73

0.002

Tobacco use disorder

1.29

1.00 - 1.67

0.05

Smoking related disorder

2.22

1.52 - 3.24

<0.001

Rheumatologic disease

1.86

1.10 - 3.13

0.02

Ota 2016 [60]

BMI ≥ 25

4.79

1.64 - 13.97

0.004

Pettke 2016 [87]

Age ≥ 80 years

0.66

0.57 - 0.78

<0.001

Tanner 2011 [67]

NNIS score 1

3.97

1.16 - 13.54

0.03

NNIS score 2

33.75

4.34 - 262.28

<0.001

Teija-Kaisa 2012 [68]

AMP 30 - 60 mins before incision

2.64

1.05 - 6.65

0.04

Intra-operative phase

Angarita 2011 [26]

Radical vs BCS

17.62

5.13 - 60.47

<0.001

Chattha 2017 [75]

Mastectomy weight ≥ 500 g

2.98

1.78 - 5.01

<0.001

Cordeiro 2016 [77]

Overnight stay vs same-day stay

1.48

1.24 - 1.76

<0.001

Stay ≥ 2 days vs same-day stay

2.16

1.79 - 2.61

<0.001

Franchelli 2012 [40]

Tumour stage II-IV

5.29

1.35 - 20.66

0.02

Gil-Londoño 2017 [80]

Radical mastectomy

2.73

1.43 - 5.19

0.002

Gülçelık 2017 [83]

IORT

12.97

1.57 - 107.18

0.02

Olsen 2015 [56]

Needle localisation

0.78

0.66 - 0.92

0.003

Parikh 2016 [85]

Ambulatory surgery centre vs outpatient

0.35

0.28 - 0.44

<0.001

Winocour 2015 [72]

Operative time ≥ 2.5 hours

2.19

1.72 - 2.80

<0.001

Post-operative phase

Franchelli 2012 [40]

Radiotherapy after surgery before infection

4.08

1.03 - 16.23

0.05

Leyngold 2012 [49]

Cellulitis

242.67

35.42 - 1662.23

<0.001

Wound dehiscence

10.06

2.65 - 38.27

<0.001

Wound necrosis

8.74

2.32 - 32.95

<0.001

Olsen 2016 [57]

Home healthcare

0.72

0.58 - 0.89

0.002

Olsen 2017 [58]

SSI after SR + Implant IR

4.58

3.23 - 6.50

<0.001

Ota 2016 [60]

Seroma aspiration

15.92

6.16 - 41.11

<0.001

Pellino 2014 [86]

NPWT

0.22

0.05 - 0.93

0.04