Univariate analysis

Multivariate analysis

Variables

No (%)

HR

P value

HR

P value

(95% CI)

(95% CI)

Age

<50 years

53 (20%)

1 (Referent)

1 (Referent)

>50 years

211 (80%)

0.70

0.49

0.51

0.25

(0.25 - 1.92)

(0.17 - 1.59)

Nuclear grade

1 - 2

179 (68%)

1 (Referent)

1 (Referent)

3

85 (32%)

2.93

0.017

3.10

0.031

(1.21 - 7.09)

(1.11 - 8.69)

Lymphatic invasion

Negative

134 (51%)

1 (Referent)

1 (Referent)

Positive

130 (49%)

2.43

0.069

1.27

0.71

(0.93 - 6.34)

(0.36 - 4.56)

Venous invasion

Negative

195 (74%)

1 (Referent)

1 (Referent)

Positive

69 (26%)

1.39

0.47

0.55

0.31

(0.57 - 3.41)

(0.17 - 1.74)

Estrogen receptor

Negative

39 (15%)

1 (Referent)

1 (Referent)

Positive

225 (85%)

0.32

0.021

0.30

0.14

(0.12 - 0.84)

(0.06 - 1.50)

Progesterone receptor

Negative

69 (26%)

1 (Referent)

1 (Referent)

Positive

195 (74%)

0.41

0.054

0.72

0.65

(0.17 - 1.10)

(0.18 - 2.97)

HER2

Negative

218 (83%)

1 (Referent)

1 (Referent)

Positive

46 (17%)

1.48

0.49

0.71

0.56

(0.49 - 4.45)

(0.22 - 2.28)

Lymph node involvement

Negative

185 (70%)

1 (Referent)

1 (Referent)

Positive

79 (30%)

3.32

0.0086

3.04

0.038

(1.36 - 8.13)

(1.07 - 8.67)

Tumor size

<20mm

125 (47%)

1 (Referent)

1 (Referent)

>20mm

139 (53%)

4.35

0.0091

3.01

0.070

(1.44 - 13.14)

(0.91 - 10.6)

PLR

<162.3

189 (72%)

1 (Referent)

1 (Referent)

>162.3

75 (28%)

2.39

0.052

3.60

0.012

(0.99 - 5.75)

(1.32 - 9.78)