Number of cycles of trastuzumab administration over one year

17 cycles (Assumption based on practice at the participating sites)

Consumables utilisation and unit costs

Site estimate

Drug doses and unit costs

Roche (Malaysia), drug package insert [17] [18] [32]

Usage of leftover IV drugs

All leftover IV trastuzumab is shared and used (Assumption based on practice at the participating sites)

Human resource utilisation (average working hours)

Site estimate

Unit cost of human resources

Government salary scales [33]

Anonymous patient weights

Data from study sites

Patient treatment time

Site estimate

Median female wage rate

RM8.22 per hour [34]